Dengue facts worldwide …
Total Cases: Over 5 million reported across 106 countries/territories. Total Deaths: Over 3,000 fatalities confirmed globally. Case Distribution: The Americas remains the hardest-hit region, accounting for over 80% of reported cases.
Public health officials issued alerts regarding the resurgence of Serotype 3 (DENV-3). Because many populations hadn't been exposed to this strain for years, "immunological naïveté" led to higher rates of severe dengue and hospitalisation.
Takeda’s Qdenga (TAK-003) vaccine saw its widest distribution yet, with 18.6 million doses distributed across 11 endemic countries by September 2025. Long-term data released in November 2025 showed the vaccine provides protection for at least 7 years.
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